Semaglutide dosing chart
The table below shows the full semaglutide titration schedule from 0.25 mg to 2.4 mg with pre-calculated syringe units for the three most common vial concentrations. Find your current dose, find your concentration, and read the units to draw.
| Weeks | Dose (mg) | Dose (mcg) | 2.5 mg/ml | 5 mg/ml | 10 mg/ml |
|---|---|---|---|---|---|
| 1-4 | 0.25 mg | 250 | 10 units | 5 units | 2.5 units |
| 5-8 | 0.5 mg | 500 | 20 units | 10 units | 5 units |
| 9-12 | 1 mg | 1000 | 40 units | 20 units | 10 units |
| 13-16 | 1.7 mg | 1700 | 68 units | 34 units | 17 units |
| 17+ | 2.4 mg | 2400 | 96 units | 48 units | 24 units |
Units shown are for a U-100 insulin syringe (100 units = 1 ml).
How to read this chart
The three right columns show units to draw on a U-100 insulin syringe at each concentration. Concentration is the amount of semaglutide per milliliter of solution after you reconstitute the vial with bacteriostatic water. Higher concentration means fewer units for the same dose.
The math: divide your dose in mg by the concentration in mg/ml to get the volume in ml, then multiply by 100 to convert to syringe units. Example: 1.0 mg divided by 2.5 mg/ml equals 0.4 ml, times 100 equals 40 units. If your vial is 5 mg/ml instead, the same 1.0 mg dose is only 20 units. The dose stays the same, the volume changes based on how concentrated your solution is.
Reconstitution examples
Your concentration depends on the vial size and how much bacteriostatic water you add. Here are the most common setups:
2.5 mg/ml
3 mg vial + 1.2 ml BAC water
2.5 mg/ml
5 mg vial + 2 ml BAC water
5 mg/ml
5 mg vial + 1 ml BAC water
10 mg/ml
10 mg vial + 1 ml BAC water
If you have a different vial size or want to use a different water volume, the semaglutide calculator will handle any combination.
Dosing tips
Missed dose
If fewer than 3 days have passed since your scheduled injection day, take it as soon as you remember. If more than 3 days have passed, skip the missed dose and take your next one on the regular day. Do not inject two doses in the same week.
Injection sites
Subcutaneous injection into the abdomen (at least 2 inches from the navel), front of the thigh, or back of the upper arm. Rotate sites each week to reduce irritation. Clean the skin with an alcohol swab before injecting.
Storage
Reconstituted semaglutide goes in the refrigerator at 2-8 C (36-46 F). Keep it upright, away from light, and use it within 28 days. Do not freeze. If you see particles, cloudiness, or discoloration, discard the vial.
Frequently asked questions
How many units of semaglutide should I inject per week?
It depends on your dose and your vial concentration. At 2.5 mg/ml, a 0.25 mg dose is 10 units, 0.5 mg is 20 units, 1.0 mg is 40 units, 1.7 mg is 68 units, and 2.4 mg is 96 units on a U-100 insulin syringe. If your concentration is 5 mg/ml, cut those numbers in half.
What is the standard semaglutide titration schedule?
Start at 0.25 mg weekly for 4 weeks, increase to 0.5 mg for weeks 5 through 8, then 1.0 mg for weeks 9 through 12, 1.7 mg for weeks 13 through 16, and 2.4 mg from week 17 onward. Each step lasts at least 4 weeks so your body adjusts before the next increase.
Can I stay on a lower semaglutide dose instead of titrating to 2.4 mg?
Yes. Many people stay at 1.0 mg or 1.7 mg if they are losing weight and tolerating the dose well. The 2.4 mg target comes from the Wegovy label, but your clinician may keep you at a lower dose based on your response and side effects.
What happens if I miss a semaglutide dose?
If fewer than 3 days have passed since your scheduled injection, take the missed dose as soon as you can. If more than 3 days have passed, skip it and take your next dose on the regular day. Do not double up.
How do I calculate semaglutide units from mg?
Divide your dose in mg by your vial concentration in mg/ml, then multiply by 100. For example, 1.0 mg divided by 2.5 mg/ml equals 0.4 ml, times 100 equals 40 units. The concentration depends on how much bacteriostatic water you added when you reconstituted the vial.
Calculator
Semaglutide reconstitution calculator
Enter your exact vial size and BAC water volume to get the units for any dose
This page is not medical advice. Semaglutide is a prescription drug (brand names Wegovy and Ozempic). The dosing schedule above follows the Wegovy label titration but your clinician may adjust it based on your response and side effects. Work with a qualified provider before starting, changing, or stopping any semaglutide protocol. Read the full disclaimer.