Semaglutide (Ozempic / Wegovy) dose calculator
GLP-1 receptor agonist (94% structural homology to human GLP-1, Lau J Med Chem 2015, PMID 26308095). Reduces appetite and slows gastric emptying. Dosed weekly with gradual titration up from 0.25 mg per the Wegovy label (FDA 2024). STEP 1 trial (Wilding NEJM 2021, PMID 33567185) reported ~14.9% mean weight loss at 68 weeks on 2.4 mg.
By the DosingCalc editorial team. Numbers and dose ranges are checked against the sources listed on our editorial standards page.
Half-life
6.9 days
Storage
2-8°C refrigerated
Route
subcutaneous
Shelf life
28 days
Common side effects
nausea, vomiting, diarrhea, constipation, pancreatitis (rare but serious), thyroid C-cell tumors (boxed warning)
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Bacteriostatic Water
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Semaglutide dosing chart
Full titration schedule from 0.25 mg to 2.4 mg with pre-calculated units for every vial size
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Frequently asked questions
How much bacteriostatic water should I add to Semaglutide?
For a 5mg vial of Semaglutide, add 2ml of bacteriostatic water. This concentration works well with a standard insulin syringe.
What is the typical Semaglutide dosage?
Typical research dosages for Semaglutide range from 250 to 2400 mcg, administered 1x weekly.
How long does reconstituted Semaglutide last?
Reconstituted Semaglutide should be stored at 2-8°C refrigerated and used within 28 days. Unreconstituted vials can be stored for up to 24 months.