Semaglutide (Ozempic / Wegovy) dose calculator
GLP-1 receptor agonist (94% structural homology to human GLP-1, Lau J Med Chem 2015, PMID 26308095). Reduces appetite and slows gastric emptying. Dosed weekly with gradual titration up from 0.25 mg per the Wegovy label (FDA 2024). STEP 1 trial (Wilding NEJM 2021, PMID 33567185) reported ~14.9% mean weight loss at 68 weeks on 2.4 mg.
By the DosingCalc editorial team. Numbers and dose ranges are checked against the sources listed on our editorial standards page.
Medically reviewed by Elena Whitmore, PharmD.
Half-life
6.9 days
Storage
2-8°C refrigerated
Route
subcutaneous
Shelf life
28 days
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Common side effects
nausea, vomiting, diarrhea, constipation, pancreatitis (rare but serious), thyroid C-cell tumors (boxed warning)
What you need
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Syringes
30G 1cc 1/2" Insulin Syringes
30-gauge needle, 1ml capacity, 1/2" length. Most versatile size for peptide dosing. Common brands: Brandzig, Easy Touch, Care Touch.
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30G 0.5cc Insulin Syringes
0.5ml capacity with finer markings and bold graduation numbers. Better for small doses under 50 units.
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Bacteriostatic Water
Storage
Mini Fridge for Peptide Storage
Dedicated peptide fridge keeps vials at 2-8°C without opening the kitchen door 12 times a day. The Cooluli 4L is the staple pick.
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3mL Peptide Vial Storage Case
10-slot transparent holder for 1-3mL vials. Keeps reconstituted peptides organized in the fridge and visible at a glance.
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Reference
Semaglutide dosing chart
Full titration schedule from 0.25 mg to 2.4 mg with pre-calculated units for every vial size
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Frequently asked questions
How much bacteriostatic water should I add to Semaglutide?
For a 5mg vial of Semaglutide, add 2ml of bacteriostatic water. This concentration works well with a standard insulin syringe.
What is the typical Semaglutide dosage?
Typical research dosages for Semaglutide range from 250 to 2400 mcg, administered 1x weekly.
How long does reconstituted Semaglutide last?
Reconstituted Semaglutide should be stored at 2-8°C refrigerated and used within 28 days. Unreconstituted vials can be stored for up to 24 months.
How do I calculate my Semaglutide dose?
Divide your target dose by the concentration to get the volume, then multiply by 100 for units on a U-100 insulin syringe. For example, a 5mg vial in 2ml of bacteriostatic water gives 2500 mcg/ml. The calculator above does this automatically once you enter your vial size, water volume, and desired dose.
How many units of Semaglutide should I draw on an insulin syringe?
On a U-100 insulin syringe, 1 unit equals 0.01 ml regardless of the barrel size (0.3ml, 0.5ml, or 1ml). Enter your reconstitution details in the calculator to see the exact number of units to draw for your dose.