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DosingCalc

HGH reconstitution calculator

Recombinant human growth hormone (somatropin). Adult GH-deficiency replacement is typically 0.2-0.6 mg/day (~0.6-1.8 IU) per AACE 2019 guidelines (Yuen, Endocr Pract 2019, PMID 31760818). Doses above ~2 IU/day are supraphysiologic and used off-label for body composition. WHO IS 98/574 reference standard: 3 IU per mg somatropin, so 1 IU ≈ 333 mcg. Contraindicated in active malignancy, proliferative retinopathy, and acute critical illness (Genotropin USPI §4; Takala, NEJM 1999, PMID 10477776 for ICU mortality signal).

By the DosingCalc editorial team. Numbers and dose ranges are checked against the sources listed on our editorial standards page.

Half-life

3.5 hours

Storage

2-8°C refrigerated

Route

subcutaneous

Shelf life

21 days

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Common side effects

joint pain, water retention, carpal tunnel, numbness/tingling, elevated blood sugar

Common vial sizes

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Frequently asked questions

How much bacteriostatic water should I add to HGH?

For a 10mg vial of HGH, add 2ml of bacteriostatic water. This concentration works well with a standard insulin syringe.

What is the typical HGH dosage?

Typical research dosages for HGH range from 200 to 4000 mcg, administered 1x daily.

How long does reconstituted HGH last?

Reconstituted HGH should be stored at 2-8°C refrigerated and used within 21 days. Unreconstituted vials can be stored for up to 24 months.