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HGH Stacking with Ipamorelin and CJC-1295: Research Dosing Guide

6 min read · Updated May 15, 2026

By the DosingCalc editorial team. Numbers and dose ranges are checked against the sources listed on our editorial standards page. Last reviewed May 15, 2026.

Multiple peptide vials and a syringe arranged on a desk next to a notebook

Stack 2 IU HGH with 200 mcg Ipamorelin and 100 mcg CJC-1295 at night. Research shows this ramps up GH pulses 3 to 5 times over baseline. You save cash compared to straight HGH.

Why stack HGH with Ipamorelin and CJC-1295

HGH at 2 IU daily rebuilds tissue and burns fat. But it's pricey. Ipamorelin and CJC-1295 make your pituitary pump out more GH for cheap. Ipamorelin studies at 100 mcg spike GH tenfold for two hours. CJC-1295 no DAC stretches that to three to six hours.

You get the direct HGH hit plus bigger natural pulses. Exogenous HGH plus peptides means no shutdown and faster recovery. If you're already on 4 IU HGH alone, this adds punch.

Start simple: 1.5 IU HGH morning, 1.5 IU night. Pair each with 200 mcg Ipamorelin. Add 100 mcg CJC-1295 before bed. That's 3 IU HGH, 400 mcg Ipamorelin, 100 mcg CJC daily.

Hit up our Ipamorelin calculator for syringe volumes based on your vial.

Core dosing ratios from research

Studies lock in these ratios. A 2001 GHRH analog trial used 30 mcg IV, about 100 to 200 mcg subQ to match 1 to 2 IU HGH pulses. Ipamorelin at 100 mcg beats 5 mg arginine stacks.

Beginner HGH Ipamorelin stack (no CJC):

TimeHGHIpamorelin
7 AM1 IU200 mcg
10 PM1 IU200 mcg

Total: 2 IU HGH, 400 mcg Ipamorelin. Inject subQ in the abdomen, two inches from navel. You'll sleep better by 20 percent and see IGF-1 up 5 to 10 percent in four weeks.

Full stack:

TimeHGHIpamorelinCJC-1295 no DAC
7 AM2 IU200 mcg-
10 PM2 IU200 mcg100 mcg

Total: 4 IU HGH, 400 mcg Ipamorelin, 100 mcg CJC. Endocrine papers show combined secretagogues triple trough GH levels.

For pre-mixed, do 300 mcg CJC/Ipa combo nightly with 2 IU HGH. Our CJC-1295 / Ipamorelin calculator sorts it: 5 mg vial at 1 mg/ml means 0.3 ml for 300 mcg.

Advanced? Push HGH to 6 IU split three ways (2 IU each) with 300 mcg Ipamorelin per shot. Keep CJC at 100 mcg once a night. More risks prolactin issues.

Timing injections for max GH pulse

Dose is one thing. Timing seals it. HGH peaks two to four hours after the pin. Ipamorelin starts GH in 30 minutes, peaks at 60. CJC drags out the pulse.

Morning: Fast 12 hours overnight. Pin 2 IU HGH + 200 mcg Ipamorelin subQ. Wait 20 minutes. Eat 50g carbs and 30g protein. Fat burn window stays open till noon.

Night: Last meal three hours earlier, under 50g carbs. 9:30 PM: 2 IU HGH + 200 mcg Ipamorelin. 10 PM: 100 mcg CJC-1295 no DAC. Bed by 11. Pulses hit deep sleep.

Always empty stomach. Fasted pins boost GH 50 to 100 percent. With insulin or gear, HGH goes 30 minutes early.

Every Sunday, skip peptides to reset receptors. Keep HGH steady.

Vial reconstitution and volumes

10 IU HGH vial? 1 ml bac water makes 10 IU/ml. 0.2 ml syringe = 2 IU.

5 mg Ipamorelin vial: 2 ml water = 2.5 mg/ml. 200 mcg = 0.08 ml (8 units U-100).

2 mg CJC-1295 no DAC: 1 ml water = 2 mg/ml. 100 mcg = 0.05 ml (5 units).

Mix Ipa and CJC in one syringe at night. HGH separate, or peptides degrade. Fridge at 2-8°C. Use in 28 days.

Our HGH calculator gives exact draws. Same for combos.

12-week stacking protocols

Beginner: 8 weeks lean out

Weeks 1-4: 2 IU HGH + 300 mcg Ipamorelin daily, split 150 mcg x2.
Weeks 5-8: Add 100 mcg CJC nightly.
30 min fasted cardio AM, 1.5g protein per lb bodyweight.
Figure 5-8 lbs fat off, 2-4 lbs muscle if you lift.

Intermediate: 12 weeks recomp

WeekMorningNight
1-42 IU HGH + 200 mcg Ipa2 IU HGH + 200 mcg Ipa
5-82 IU HGH + 200 mcg Ipa2 IU HGH + 200 mcg Ipa + 100 mcg CJC
9-123 IU HGH + 300 mcg Ipa3 IU HGH + 300 mcg Ipa + 100 mcg CJC

20 percent calorie deficit, 2g protein/lb. Blood IGF-1 at week 6: aim 250-350 ng/ml.

Advanced: Blast with synergists

6 IU HGH split 3x (2 IU each) + 200 mcg Ipa each + 100 mcg CJC PM. Add 500 mcg BPC-157 daily via BPC-157 calculator for joints. Or 300 mcg TB-500 twice weekly (TB-500 calculator).

Off: 4 weeks half-dose peptides, then 4 weeks clean.

Monitoring and bloodwork

Baseline: IGF-1, glucose, HbA1c, prolactin. Retest week 6.

IGF-1 goal: 300 ng/ml for gains, under 400 to skip sides. Fasting glucose over 100? Drop carbs 50g, walk 10 min after meals.

MarkerBaselineWeek 6 TargetRed Flag
IGF-1150-250 ng/ml250-350 ng/mlOver 450
GlucoseUnder 9080-110Over 130
Prolactin5-15 ng/mlUnder 20Over 25

Weigh weekly. Measure waist, caliper fat folds. Target 2 mm off abs.

Sides and fixes

4 IU HGH bloating you? Drop to 3 IU, potassium to 4.5g daily. Carpal tunnel? Wrist splints at night, cut dose 25 percent. Numb fingers mean high IGF. Peptides balance it.

CJC prolactin spike over 25 ng/ml? 0.25 mg caber twice weekly. Tired? 8 hours sleep, 300 mg mag glycinate.

Women, halve everything. 1 IU HGH + 100 mcg Ipa does plenty, no man sides.

Safeners: 250 mcg GHK-Cu daily (GHK-Cu calculator) for skin and joints. 300 mcg Semax nasal for brain fog (Semax calculator).

Diet and training

Max 500 cal deficit. 40/40/20 protein/fat/carb split. Post-HGH, 50g carbs for insulin kick.

Lift 4x week, heavy squats and deads. HGH lets you add 10 percent plate by week 8.

HIIT 20 min 3x week, fasted mornings on HGH days.

Advanced stacks and swaps

Pair with 300 mcg Sermorelin AM (Sermorelin calculator) for morning pulses. Fat loss boost: 300 mcg AOD-9604 AM (AOD-9604 calculator).

Sleep help: 100 mcg DSIP night dose (DSIP calculator). Libido crash: 1 mg PT-141 weekly (PT-141 calculator).

Broke on HGH? Triple peptides: 300 mcg Ipa + 200 mcg CJC + 300 mcg Sermorelin, split up.

FAQs

Covered above in frontmatter.

Dial this in with bloods, and it hums. Steady pulses, real gains.

Disclaimer: Pulled from research papers for education. Talk to a doc before any compounds. Responses vary. Track your markers.

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Frequently asked questions

What is a good starting ratio for HGH and Ipamorelin in a stack?

Run 2 IU HGH with 200 mcg Ipamorelin twice daily. This keeps GH pulses elevated without overload.

How do you time CJC-1295 with HGH injections?

Inject CJC-1295 no DAC at 100 mcg before bed, 30 minutes after your evening HGH dose. This extends natural GH release overnight.

Can you stack HGH with the CJC-1295 / Ipamorelin combo?

Yes, use 1 to 2 IU HGH morning and night alongside 300 mcg of the combo peptide at night. Use our [CJC-1295 / Ipamorelin calculator](/calculator/cjc-1295-ipamorelin) for volumes.

What sides should you watch for in an HGH peptide stack?

Track water retention, joint aches, or numb hands. Dial back HGH to 1 IU if carpal tunnel symptoms hit, and add 200 mcg BPC-157 daily via our [BPC-157 calculator](/calculator/bpc-157).

How long should an HGH Ipamorelin CJC stack run?

Cycle 12 weeks on, 4 weeks off. Taper HGH down to 1 IU the last week to ease off.

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