Cagrilintide dose calculator
Long-acting amylin analog (AM833) from Novo Nordisk, given once weekly by subcutaneous injection with an elimination half-life of 159-195 hours (Enebo 2021, Lancet, PMID 33894838). In a phase 2 monotherapy dose-finding trial, weekly cagrilintide titrated to 4.5 mg produced about 10.8% mean weight loss at 26 weeks versus 3.0% with placebo (Lau 2021, Lancet, PMID 34798060). It is the amylin component of the fixed-dose combination CagriSema (with semaglutide 2.4 mg), which reached 22.7% on-treatment weight loss at 68 weeks in the phase 3 REDEFINE 1 trial (Garvey 2025, NEJM, PMID 40544433). Standalone cagrilintide remains investigational and is not FDA-approved.
By the DosingCalc editorial team. Numbers and dose ranges are checked against the sources listed on our editorial standards page.
Half-life
7.4 days
Storage
2-8°C refrigerated
Route
subcutaneous
Shelf life
28 days
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Common side effects
nausea, vomiting, diarrhea, constipation, decreased appetite, injection site reactions
What you need
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Syringes
30G 1cc 1/2" Insulin Syringes
30-gauge needle, 1ml capacity, 1/2" length. Most versatile size for peptide dosing. Common brands: Brandzig, Easy Touch, Care Touch.
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30G 0.5cc Insulin Syringes
0.5ml capacity with finer markings and bold graduation numbers. Better for small doses under 50 units.
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Bacteriostatic Water
Storage
Mini Fridge for Peptide Storage
Dedicated peptide fridge keeps vials at 2-8°C without opening the kitchen door 12 times a day. The Cooluli 4L is the staple pick.
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3mL Peptide Vial Storage Case
10-slot transparent holder for 1-3mL vials. Keeps reconstituted peptides organized in the fridge and visible at a glance.
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Frequently asked questions
How much bacteriostatic water should I add to Cagrilintide?
For a 5mg vial of Cagrilintide, add 1ml of bacteriostatic water. This concentration works well with a standard insulin syringe.
What is the typical Cagrilintide dosage?
Typical research dosages for Cagrilintide range from 250 to 2400 mcg, administered 1x weekly.
How long does reconstituted Cagrilintide last?
Reconstituted Cagrilintide should be stored at 2-8°C refrigerated and used within 28 days. Unreconstituted vials can be stored for up to 24 months.