Retatrutide dose calculator

Investigational triple GIP/GLP-1/glucagon receptor agonist from Eli Lilly. Phase 2 trial (Jastreboff, NEJM 2023, PMID 37366315) reported up to ~24% mean body weight loss at 12 mg weekly over 48 weeks. Titrate from 2 mg to reduce GI side effects. Phase 3 TRIUMPH program is ongoing.

By the DosingCalc editorial team. Numbers and dose ranges are checked against the sources listed on our editorial standards page.

Half-life

6.0 days

Storage

2-8°C refrigerated

Route

subcutaneous

Shelf life

28 days

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Common side effects

nausea, vomiting, diarrhea, constipation, dysesthesia (skin tingling/burning), injection site reactions, pancreatitis (rare but serious)

What you need

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Syringes

30G 1cc 1/2" Insulin Syringes

30-gauge needle, 1ml capacity, 1/2" length. Most versatile size for peptide dosing. Common brands: Brandzig, Easy Touch, Care Touch.

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Bacteriostatic Water

Bacteriostatic Water 30mL

0.9% benzyl alcohol preserved water for reconstituting lyophilized peptides. Multi-dose vials, typically 30mL.

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Alcohol Swabs

Sterile Alcohol Prep Pads

70% isopropyl alcohol. Individually wrapped, medical-grade. Use before every injection.

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Sharps Disposal

1 Quart Sharps Container

CDC-certified, puncture-resistant with flip-up lid. A 1-quart container lasts months for personal use.

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Storage

Mini Fridge for Peptide Storage

Dedicated peptide fridge keeps vials at 2-8°C without opening the kitchen door 12 times a day. Cooluli, AstroAI, and Chefman are the common picks.

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Common vial sizes

5mg vial 10mg vial 15mg vial

Related peptides

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250-500 mcg · 1x daily, morning on empty stomach

MOTS-c

5000-10000 mcg · 3-5x weekly

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Delve into the latest research on Retatrutide dosing strategies, including vial preparation, titration schedules, and storage recommendations from clinical studies. Educational content for researchers focusing on metabolic peptide investigations.

Frequently asked questions

How much bacteriostatic water should I add to Retatrutide?

For a 10mg vial of Retatrutide, add 2ml of bacteriostatic water. This concentration works well with a standard insulin syringe.

What is the typical Retatrutide dosage?

Typical research dosages for Retatrutide range from 2000 to 12000 mcg, administered 1x weekly.

How long does reconstituted Retatrutide last?

Reconstituted Retatrutide should be stored at 2-8°C refrigerated and used within 28 days. Unreconstituted vials can be stored for up to 24 months.