MOTS-c dose calculator

Mitochondria-derived peptide encoded in mtDNA. Studied for metabolic regulation, exercise mimicry, and insulin sensitivity. Human dosing is not established in published trials; the range below reflects community protocols, not clinical data.

By the DosingCalc editorial team. Numbers and dose ranges are checked against the sources listed on our editorial standards page.

Half-life

1.5 hours

Storage

2-8°C refrigerated

Route

subcutaneous

Shelf life

21 days

Common side effects

injection site irritation, nausea

What you need

This page contains affiliate links. We may earn a commission at no extra cost to you.

Syringes

30G 1cc 1/2" Insulin Syringes

30-gauge needle, 1ml capacity, 1/2" length. Most versatile size for peptide dosing. Common brands: Brandzig, Easy Touch, Care Touch.

via Amazon

Bacteriostatic Water

Bacteriostatic Water 30mL

0.9% benzyl alcohol preserved water for reconstituting lyophilized peptides. Multi-dose vials, typically 30mL.

via Amazon

Alcohol Swabs

Sterile Alcohol Prep Pads

70% isopropyl alcohol. Individually wrapped, medical-grade. Use before every injection.

via Amazon

Sharps Disposal

1 Quart Sharps Container

CDC-certified, puncture-resistant with flip-up lid. A 1-quart container lasts months for personal use.

via Amazon

Storage

Mini Fridge for Peptide Storage

Dedicated peptide fridge keeps vials at 2-8°C without opening the kitchen door 12 times a day. Cooluli, AstroAI, and Chefman are the common picks.

via Amazon

Common vial sizes

5mg vial 10mg vial

Related peptides

AOD-9604 Semaglutide

Related calculators

Semaglutide

250-2400 mcg · 1x weekly

Retatrutide

2000-12000 mcg · 1x weekly

Tirzepatide

2500-15000 mcg · 1x weekly

AOD-9604

250-500 mcg · 1x daily, morning on empty stomach

Compare

All weight loss peptide calculators

Semaglutide, tirzepatide, AOD-9604 and MOTS-c side by side

Learn more

MOTS-c Dosing Guide — Reconstitution, Benefits, Half-Life

MOTS-c research dosing: where the human evidence actually stands, typical preclinical protocols, reconstitution, and storage.

Frequently asked questions

How much bacteriostatic water should I add to MOTS-c?

For a 5mg vial of MOTS-c, add 2ml of bacteriostatic water. This concentration works well with a standard insulin syringe.

What is the typical MOTS-c dosage?

Typical research dosages for MOTS-c range from 5000 to 10000 mcg, administered 3-5x weekly.

How long does reconstituted MOTS-c last?

Reconstituted MOTS-c should be stored at 2-8°C refrigerated and used within 21 days. Unreconstituted vials can be stored for up to 24 months.