MOTS-c dose calculator
Mitochondria-derived peptide encoded in mtDNA. Studied for metabolic regulation, exercise mimicry, and insulin sensitivity. Human dosing is not established in published trials; the range below reflects community protocols, not clinical data.
By the DosingCalc editorial team. Numbers and dose ranges are checked against the sources listed on our editorial standards page.
Medically reviewed by Elena Whitmore, PharmD.
Half-life
1.5 hours
Storage
2-8°C refrigerated
Route
subcutaneous
Shelf life
21 days
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Common side effects
injection site irritation, nausea
What you need
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Syringes
30G 1cc 1/2" Insulin Syringes
30-gauge needle, 1ml capacity, 1/2" length. Most versatile size for peptide dosing. Common brands: Brandzig, Easy Touch, Care Touch.
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30G 0.5cc Insulin Syringes
0.5ml capacity with finer markings and bold graduation numbers. Better for small doses under 50 units.
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Bacteriostatic Water
Storage
Mini Fridge for Peptide Storage
Dedicated peptide fridge keeps vials at 2-8°C without opening the kitchen door 12 times a day. The Cooluli 4L is the staple pick.
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3mL Peptide Vial Storage Case
10-slot transparent holder for 1-3mL vials. Keeps reconstituted peptides organized in the fridge and visible at a glance.
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Frequently asked questions
How much bacteriostatic water should I add to MOTS-c?
For a 5mg vial of MOTS-c, add 2ml of bacteriostatic water. This concentration works well with a standard insulin syringe.
What is the typical MOTS-c dosage?
Typical research dosages for MOTS-c range from 5000 to 10000 mcg, administered 3-5x weekly.
How long does reconstituted MOTS-c last?
Reconstituted MOTS-c should be stored at 2-8°C refrigerated and used within 21 days. Unreconstituted vials can be stored for up to 24 months.
How do I calculate my MOTS-c dose?
Divide your target dose by the concentration to get the volume, then multiply by 100 for units on a U-100 insulin syringe. For example, a 5mg vial in 2ml of bacteriostatic water gives 2500 mcg/ml. The calculator above does this automatically once you enter your vial size, water volume, and desired dose.
How many units of MOTS-c should I draw on an insulin syringe?
On a U-100 insulin syringe, 1 unit equals 0.01 ml regardless of the barrel size (0.3ml, 0.5ml, or 1ml). Enter your reconstitution details in the calculator to see the exact number of units to draw for your dose.