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DosingCalc

5 mg Tirzepatide (Mounjaro / Zepbound) reconstitution calculator

Add 2 ml of bacteriostatic water to your 5 mg vial. Enter your dose below to see how many units to draw on an insulin syringe.

By the DosingCalc editorial team. Numbers and dose ranges are checked against the sources listed on our editorial standards page.

A 5 mg vial of Tirzepatide is usually mixed with 2 ml of bacteriostatic water. That gives you a concentration of about 2.50 mg/ml. At a 5000 mcg dose, one 5 mg vial covers around 1 doses, taken 1x weekly. Tirzepatide is also commonly sold in 10mg and 15mg vials, but this page focuses on the 5mg size. The calculator above is set to the 5 mg vial. Enter your target dose (anywhere from 2500 to 15000 mcg is typical) and it shows the exact number of units to draw on an insulin syringe. After mixing, keep the vial at 2-8°C refrigerated and finish it within 28 days. Unopened, a 5 mg vial stays good for up to 24 months. When you add the water, run it down the inside wall of the vial. Swirl, do not shake.

Other Tirzepatide vial sizes

How to reconstitute 5mg Tirzepatide

  1. 1Gather supplies: 5mg Tirzepatide vial, bacteriostatic water, 2ml syringe, insulin syringe, alcohol swabs.
  2. 2Wipe the stoppers of both the peptide vial and bac water with an alcohol swab. Let dry.
  3. 3Draw 2ml of bacteriostatic water into the syringe.
  4. 4Inject the water slowly down the inside wall of the Tirzepatide vial. Do not spray directly onto the powder.
  5. 5Gently swirl the vial until the powder is fully dissolved. Never shake.
  6. 6Store at 2-8°C refrigerated. Use within 28 days. Use the calculator above to determine how many units to draw for each dose.

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