Gonadorelin reconstitution calculator
Synthetic GnRH decapeptide identical to endogenous gonadotropin-releasing hormone; pulsatile receptor stimulation triggers pituitary LH and FSH release (FDA Factrel label, NDA 017866). Plasma half-life is only ~2-10 minutes. In TRT it is used off-label to help preserve testicular volume and intratesticular testosterone during exogenous-androgen gonadotropin suppression, though no large RCTs support this specific use. Chronic non-pulsatile exposure paradoxically downregulates GnRH receptors and suppresses gonadotropins. Community TRT dosing figures are practice-based, not label-derived.
By the DosingCalc editorial team. Numbers and dose ranges are checked against the sources listed on our editorial standards page.
Medically reviewed by Elena Whitmore, PharmD.
Half-life
0.15 hours
Storage
2-8°C refrigerated
Route
subcutaneous
Shelf life
28 days
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Common side effects
headache, nausea, flushing, abdominal discomfort, lightheadedness, injection site reactions
What you need
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Syringes
30G 1cc 1/2" Insulin Syringes
30-gauge needle, 1ml capacity, 1/2" length. Most versatile size for peptide dosing. Common brands: Brandzig, Easy Touch, Care Touch.
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30G 0.5cc Insulin Syringes
0.5ml capacity with finer markings and bold graduation numbers. Better for small doses under 50 units.
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Bacteriostatic Water
Storage
Mini Fridge for Peptide Storage
Dedicated peptide fridge keeps vials at 2-8°C without opening the kitchen door 12 times a day. The Cooluli 4L is the staple pick.
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3mL Peptide Vial Storage Case
10-slot transparent holder for 1-3mL vials. Keeps reconstituted peptides organized in the fridge and visible at a glance.
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Frequently asked questions
How much bacteriostatic water should I add to Gonadorelin?
For a 2mg vial of Gonadorelin, add 2ml of bacteriostatic water. This concentration works well with a standard insulin syringe.
What is the typical Gonadorelin dosage?
Typical research dosages for Gonadorelin range from 100 to 200 mcg, administered EOD or 2-3x weekly.
How long does reconstituted Gonadorelin last?
Reconstituted Gonadorelin should be stored at 2-8°C refrigerated and used within 28 days. Unreconstituted vials can be stored for up to 24 months.
How do I calculate my Gonadorelin dose?
Divide your target dose by the concentration to get the volume, then multiply by 100 for units on a U-100 insulin syringe. For example, a 2mg vial in 2ml of bacteriostatic water gives 1000 mcg/ml. The calculator above does this automatically once you enter your vial size, water volume, and desired dose.
How many units of Gonadorelin should I draw on an insulin syringe?
On a U-100 insulin syringe, 1 unit equals 0.01 ml regardless of the barrel size (0.3ml, 0.5ml, or 1ml). Enter your reconstitution details in the calculator to see the exact number of units to draw for your dose.